Molecular modelling predicted that the two domains are linked by a flexible region and that the second EF hand in the N terminal domain is most likely the calcium ion binding site. Native gel electrophoresis demonstrated that the protein binds both calcium and manganese ions, but not cadmium, magnesium, strontium, barium, cobalt, copper(II), iron (II), […]

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Greg DiNoto, former partner and chief reative officer at Deutsch, responded enthusiastically to the idea: “Putting the client in the room for the brief is genius. It helps inspire teams, memorialize what’s most important in a living, feeling way. And it puts client and agency in real partnership, real collaboration. Results Forty nine policies were […]

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From 297 respondents providing 611 responses, researchers reported using rodents most often in the 6 20 week age range regardless of the biology being studied. The age referred to as ‘adult’ by respondents varied between 6 and 20 weeks. Practical reasons for the choice of rodent age were frequently given, with increased cost associated with […]

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Real diamond earrings have gained tremendous popularity in recent years, perhaps most noticeably with the advent of the hip hop scene and the popularity of bling as a fashion statement. Although many jewelers have jumped onto the bling bandwagon, just as many have decided to specialize in this phenomenon. Diamond earrings are available today in […]

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Just as radio men and they were mostly men in advertising agencies sold radio to their colleagues, networks proselytized for radio among advertisers, potential sponsors of programs. Broadcasters, who made their income primarily by providing facilities and leasing airtime, were thus constantly wooing advertisers. A document produced by NBC in 1929 stated boldly that “because […]

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Whole genome sequencing of pathogens from multiple hosts in an epidemic offers the potential to investigate who infected whom with unparalleled resolution, potentially yielding important insights into disease dynamics and the impact of control measures. We considered disease outbreaks in a setting with dense genomic sampling, and formulated stochastic epidemic models to investigate person to […]

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